I wouldnt say that... it's like STD's, it only takes once. If you're body reacts differently to the drug it really doesnt matter if you've been doing it you're whole life, or if you've only done it once. You can never tell. Thats one of the reasons I stay away from anything like that... drugs, alcohol, hell... I dont even like taking aspirin when I have a headache, thats how anti drugs I am.... you're literally risking you're life for a high that you dont really need.
I don't wanna take anything that affects my mind like that.. I'm very much not into having drugs as well.. no antibiotics..no aspirin(kills ya liver) and all that..their are often natural and herbal remedies to most of these things...